Cyclops - Score 30,000 or higher, protect him and the civilians and defeat Scorcher in his bonus mission
Deadpool - Complete the Washington D.C. level.
Gambit - Score 30,000 or higher, obtain as many data discs as possible, defeat as many enemies as possible and go to the exit in his bonus mission
Green Goblin - Defeat Green Goblin and Venom at the end of Wakanda Act 3.
Hulk - Collect all five Gamma Regulators.
Iron Fist - Choose the Rebel side.
Jean Grey - Collect all five M'Kraan Shards.
Ms. Marvel - complete the New York City level.
Nick Fury - Complete the game.
Songbird - Choose the Register side.
Storm - win 25,000 coins while standing in Thor's way.
The Thing - Score 15,000 or higher, defeat the Lizard and all other enemies in 9 minutes or less on his bonus mission
Thor - Collect all five Asgardian Runes.
Venom - Defeat Green Goblin and Venom at the end of Wakanda Act 3.